Are you interested in studying an important topic in depth?

Using time-of-flight secondary ion mass spectrometry to probe surface complexes of relevance for biocorrosion processes

Are you interested in studying an important topic in depth? Apply for grad studies with professors Yolanda Hedberg and Heng-Yong Nie at the Department of Chemistry and Surface Science Western!

We are seeking candidates with background in mass spectrometric analyses, peak analyses, and/or relevant physics or programming skills to analyze large mass spectra.

The project investigates interactions of biomolecules, such as amino acids, peptides, or proteins, with metallic surfaces, such as biomedical implant materials, steel, and stainless steel. These interfacial processes are important for the biocorrosion and biodegradation processes of these materials in biological environments, such as the human body or soil. Time-of-flight secondary ion mass spectrometry is a powerful method to detect small amounts of molecules within the outermost 2 nm of a surface. By accurate peak analysis and imaging, surface complexes and molecules can be identified and semi-quantified. By using principal component analysis, many peaks and spectra can be compared and information on biomolecule adsorption/binding and orientation can be obtained.



Prof. Yolanda Hedberg (Dept. Chemistry and Surface Science Western) and Prof. Heng-Hong Nie (Surface Science Western and Department of Physics and Astronomy), Western University, London, Ontario